Argireline Dermik are two peptides help improve the appearance of photo aged skin especially when wrinkles and fine expression lines are present. These peptides work best in the upper 1/3 (third) of the face and crow's feet.
Presentation: 10 ampoules x 2ml (20ml) or 20 ampoules x 2ml (40ml)
Indications
-
Wrinkles, Crow's Feet and Fine Expression Lines
How to Use
Argireline Dermik can be applied by means of:
- Virtual Mesotherapy with Electroporation.
- Iontophoresis (Galvanic Current).
- Radiofrequency.
- MicroNeedling with dermapen or dermarollers.
- Topical Application Post-Peeling.
- Topical Application Post-Microdermabrasion.
- Topical Application with massage.
Results can usually be seen after consistent use.
Ingredients
Argireline (Acetyl Hexapeptide-8) and Leuphasyl (Pentapeptide-18)
Argireline, also known as Acetyl Hexapeptide-8, is a synthetic peptide used in skincare products for its anti-aging wrinkle relaxing properties.
Key Information about Argireline:
1. Mechanism of Action
- Argireline works by inhibiting the release of neurotransmitters that cause facial muscle contractions.
- This combats the appearance of dynamic wrinkles, particularly around the eyes and forehead, by preventing the skin from folding as much during expressions.
2. Benefits
- Improves and softens the aspect of fine lines and wrinkles, especially expression lines.
- Non-invasive alternative
- Improves skin texture and smoothness.
3. Usage
- Commonly found in serums, creams, and eye treatments.
- Typically used in concentrations of 5–10% for optimal results.
4. Side Effects
- Generally well-tolerated with a low risk of irritation.
- Some people may experience mild redness or tingling, especially with higher concentrations or sensitive skin.
5. Efficacy
- Results can usually be seen with consistent use.
- Works best as a preventative and mild treatment for early signs of aging.
6. Common Product Examples
- The Ordinary Argireline Solution 10%
- Matrixyl and Argireline combinations
- Various peptide-based anti-aging serums
What is Leuphasyl?
INCI Name: Pentapeptide-18
It mimics the natural mechanism of enkephalins, which are neurotransmitters that reduce nerve cell excitability. Often used in combination with Argireline for a synergistic effect in relaxing facial muscles.
💡 How It Works:
- Leuphasyl interferes with the neuronal signaling that triggers muscle contraction.
- By modulating acetylcholine release, it reduces muscle movement, helping to soften dynamic wrinkles (those caused by facial expressions).
✅ Benefits
Helps improve and soften the depth of expression wrinkles, particularly:
- Forehead lines
- Crow’s feet
- Frown lines
Boosts the efficacy of other peptides like Argireline when used together.
🧴 Usage and Formulation:
- Found in serums, creams, and eye treatments.
- Commonly used in peptide complexes with Argireline and Matrixyl.
- Typical concentration in skincare: 1–5%.
🛡️ Safety and Side Effects:
- Non-toxic and well-tolerated in most skin types.
- Minimal side effects: some users may notice mild irritation with higher concentrations or if used too frequently.
🔬 Scientific Insight:
- Studies suggest Leuphasyl can improve the signs of wrinkle depth with prolonged use especially when combined with Argireline.
- Works best as part of a long-term skincare routine, not as a quick fix.
🧪 Commonly Found In:
- Anti-aging formulations from brands focused on peptide-based skincare.
Often paired with:
- Argireline (Acetyl Hexapeptide-8)
- Matrixyl (Palmitoyl Pentapeptide-4 or -5)
- Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate)
NovaSkin & MediDermik
Argireline
