Glutathione Dermik

Glutathione for hyperpigmentation is a potent antioxidant that helps improve the appearance of the skin especially when melasma and PIH (post inflammatory hyper pigmentation) is present. It is also important against the free radical damage in hair follicles thus helps improve hair growth and strength.

Indications

Melasma, Chloasma, Age Spots, Uneven Tone, Post Inflammatory Hyper Pigmentation (PIH), and Hair Loss.

How to Use

Glutathione can be applied by means of: Virtual Mesotherapy with Electroporation, Iontophoresis (Galvanic Current), Radiofrequency, Cavitation, and Ultrasound MicroNeedling with dermapen or dermarollers Topical Application Post-Peeling Topical Application Post-Microdermabrasion Topical Application with massage

Ingredients

Active Ingredients: Glutathione

Mode of Action

Glutathione is a potent antioxidant, and its mechanism of action in reducing hyperpigmentation involves several pathways:

Inhibition of Tyrosinase Activity: Glutathione inhibits tyrosinase, a key enzyme involved in the production of melanin (the pigment responsible for skin color). By blocking this enzyme, glutathione decreases the synthesis of eumelanin (the darker form of melanin) and favors the production of pheomelanin, which is lighter in color.

Reduction of Oxidative Stress: Hyperpigmentation can be exacerbated by oxidative stress, which leads to an overproduction of melanin. As an antioxidant, glutathione helps neutralize free radicals and reduces oxidative stress, thereby preventing excess melanin formation.

Conversion of Melanin: Glutathione can shift the balance between eumelanin (dark pigment) and pheomelanin (light pigment). It does this by promoting the conversion of eumelanin into pheomelanin, leading to a lightening effect on the skin.

Regeneration of Antioxidant Systems: Glutathione works in synergy with other antioxidants like vitamin C and E. These antioxidants play a role in reducing pigmentation through various pathways, and glutathione helps regenerate these antioxidants, keeping them in their active form.

Detoxification: Glutathione also plays a role in detoxifying the skin cells from harmful substances that may trigger melanin production, such as heavy metals and environmental toxins.